Brain cancer remains challenging to diagnose, due to nonspecific symptoms and a lack of cost-effective tests.

Brain cancer remains challenging to diagnose, due to nonspecific symptoms and a lack of cost-effective tests. A new blood test that uses attenuated total reflection (ATR)-Fourier transform infrared (FTIR) spectroscopy in conjunction with machine learning technology, may help advance the detection of brain cancer. The patented technology, developed by a team at the University of Strathclyde, uses infrared light to produce a “bio-signature” of a blood sample and applies artificial intelligence to check for the signs of cancer. The research is published in Nature Communications in a paper titled, “Development of high-throughput ATR-FTIR technology for rapid triage of brain cancer.” In the paper, the researchers describe the development of instrumentation for the analysis of serum that is able to differentiate cancer and control patients at a sensitivity and specificity of 93.2% and 92.8%. In addition, preliminary data from the first prospective clinical validation study are presented. This research is advancing towards clinical translation and is being commercialized by ClinSpec Diagnostics. “This is the first publication of data from our clinical feasibility study and it is the f...

The Black Krystal UV quartz-bottomed microplate range from Porvair Sciences exhibit high optical transmission in the

The Black Krystal UV quartz-bottomed microplate range from Porvair Sciences exhibit high optical transmission in the 185- to 1100 nm wavelength range, making them suitable for laboratories tasked with Circular Dichroism (CD) measurements. Manufactured from ultra-pure grade black polystyrene, the plates exhibit very low autofluorescence and are resistant to solvents including alcohols, DMSO, and PBS which are widely used in CD spectroscopy. They are precision engineered to deliver a high degree of planar flatness (±100 microns) across the optical surface of all wells, enabling imaging and ultra-sensitive CD measurement of proteins and other biological molecules through the base of these plates. Black Krystal UV quartz-bottomed plates are available in ANSI/SLAS compliant 96- or 384-well formats, providing a step forward for labs seeking to make high-throughput, sensitive CD measurements. Circular Dichroism is a well-established technique for studying optical isomers and secondary structure such as alpha / double helix in biological molecules. For further information, please visit https://www.microplates.com/krystal-uv-transparent/ or contact Porvair Sciences now on +44-1978-666222...